Tyloxapol is a nonionic surfactant widely used in pharmaceutical formulations due to its unique solubilizing, emulsifying, and stabilizing properties. It is ideal for formulating challenging APIs, ensuring bioavailability, and enhancing drug delivery systems. With an established safety profile, Tyloxapol has become a preferred excipient in critical dosage forms like nebulizers, eye drops, and injectables.
Key Features
- Superior Solubilization Solubilizes poorly water-soluble APIs, making them suitable for aqueous formulations.
- Stabilization of Suspensions Prevents aggregation and sedimentation in liquid formulations, ensuring consistency.
- Emulsification Expertise Ideal for oil-in-water emulsions in topical and injectable formulations.
- Non-Irritating and Non-Toxic Safe for sensitive pharmaceutical applications like ophthalmic and respiratory formulations.
- Bioavailability Enhancement Improves API dispersion and absorption for better therapeutic efficacy.
Applications
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Respiratory Formulations
Nebulizer Solutions: Reduces surface tension for better aerosolization of APIs. Inhalation Formulations: Enhances solubility and dispersion of active drugs
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Ophthalmic Preparations
Eye Drops: Stabilizes suspensions and solubilizes hydrophobic active ingredients, ensuring clarity and consistency.
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Injectable Formulations
Parenteral Drugs: Solubilizes lipophilic APIs and improves drug stability in aqueous systems.
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Oral Dosage Forms
Oral Syrups: Effective as a solubilizer and emulsifier. Drugs: Solubilizes lipophilic APIs and improves drug stability in aqueous systems.
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Topical Dosage Forms
Creams and Gels: Ensures uniform distribution of active ingredients
Regulatory Complaince
- USP-NF • BP • IP • EP
- DMF
- EXCiPAT
- KOSHER
- HALAL
- WHO-GMP