Beta Cyclodextrin (BCD) is a cyclic oligosaccharide composed of 7 glucose units linked by α-1,4 glycosidic bonds. It is widely used in pharmaceutical, food, and cosmetic industries for its ability to form inclusion complexes with hydrophobic molecules. This enhances solubility, stability, and bioavailability, making it a versatile excipient in product formulations.
Key Features
- Improved Solubility Forms inclusion complexes with hydrophobic drugs, significantly enhancing solubility.
- Enhanced Stability Protects sensitive APIs from light, heat, & oxidation.
- Biocompatibility Non-toxic and non-irritating, suitable for parenteral, oral, and topical applications.
- Wide pH Range Effective across a broad pH range (3–12).
- Low Hemolytic Activity Safer than other cyclodextrin derivatives for intravenous use.
Applications
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Solubilizer
Increases solubility of hydrophobic APIs.
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Stabilizer
Extends shelf life by protecting APIs from environmental factors.
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Taste Masking
Used in orally administered Dosage form like syrups, lozenges, tablets, capsules, etc
Regulatory Complaince
- USP-NF • BP • IP • EP
- DMF
- EXCiPAT
- KOSHER
- HALAL
- WHO-GMP